Marine Natural Products Lab

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Malcolm Mcculloch

 Research Interests

Drug discovery
Organic synthesis
Natural products
PhD, Australian National University (2003-2006)
Bachelor of Science (1st Hons), Australian National University (1998-2002)
Bachelor of Commerce, Australian National University (1998-2002)
Work Experience
Laboratory of Prof. Chris M. Ireland, University of Utah.
Post Doctoral Fellow
Department of Chemistry, Australian National University
Laboratory Demonstrator (organic, inorganic, general)
Department of Chemistry, Australian National University
Tutor (organic, general)
  1. McCulloch, Malcolm W. B.; Coombs, Gary S.; Banerjee, Nikhil; Bugni, Tim S.; Cannon, Kendell M.; Harper, Mary Kay; Veltri, Charles A.; Virshup, David M.; Ireland, Chris M. ‘Psammaplin A as a general activator of cell based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives’, Bioorganic and Medicinal Chemistry. 2009, 17, 2189-2198.
  2. Barrow, Russell A.; McCulloch, Malcolm W. B.  ‘Linear naphtho-g-pyrones : A naturally occurring scaffold of biological importance’, Mini-Reviews in Medicinal Chemistry20099, 273-292.
  3. Bugni, Tim S.; Harper, Mary Kay; McCulloch, Malcolm W. B.; Reppart, Jason; Ireland, Chris M. ‘Fractionated marine invertebrate extract libraries for drug discovery’, Molecules 2008, 13(6), 1372-1383.
  4. McCulloch, Malcolm W. B.; Barrow, Russell A. ‘A metalation strategy for the construction of functionalized naphthalenes: the first synthesis of guieranone A’, Tetrahedron Letters2005, 46(44), 7619-7621.
  5. McCulloch, Malcolm W. B.; Barrow, Russell A. ‘Towards a synthesis of naphthalene derived natural products’, Molecules2005, 10(10), 1272-1278.